All times Central
| TIME | GAME | TV | LINE |
| 11:00 | Minnesota at Iowa |
 |
IA -13 |
| 11:00 | Ohio St. at Michigan |
 |
OSU -13 |
| 11:00 | Duke at Miami |
 |
UM -19 |
| 11:00 | Harvard at Yale |
 |
N/A |
| 11:00 | UNC at Boston College |
 |
BC -3 |
| 1:30 | Oklahoma at Texas Tech |  |
OU -6.5 |
| 1:30 | Connecticut at Notre Dame |
 |
ND -6.5 |
| 2:30 | LSU at Ole Miss |  |
MISS -4 |
| 2:30 | Penn St. at Michigan St.1 |
|
PSU -3 |
| 2:30 | Virginia at Clemson1 | |
CLEM -21 |
| 2:30 | NC State at Virgina Tech | |
VT -21 |
| 2:30 | Duke at North Carolina | |
UNC -10 |
| 2:30 | Air Force at BYU |
 |
BYU -10 |
| 2:30 | Wisconsin at Northwestern |
 |
WISC -7 |
| 3:00 |
Arizona St. at UCLA |
|
CAL -7.5 |
| 3:00 | San Diego St. at Utah |
|
UTAH -20 |
| 6:00 | Vanderbilt at Tennessee |
|
TN -21 |
| 6:30 | Cal at Stanford |
|
STAN -7 |
| 6:45 | Kansas St. at Nebraska |
|
NU -16 |
| 6:45 | Kentucky at Georgia |
|
UGA -10 |
| 7:00 | Kansas at Texas2 |
|
TX -27 |
| 7:00 | Oregon at Arizona2 | |
ORE -6 |
| 1Regional Coverage Map | 2Regional Coverage Map |